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The efficacy and safety of acute hypervolemic hemodilution guided by stroke volume variation for preventing perioperative allogeneic blood transfusion in spinal surgery

The efficacy and safety of acute hypervolemic hemodilution guided by stroke volume variation for preventing perioperative allogeneic blood transfusion in spinal surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000040895
Enrollment
Unknown
Registered
2020-12-14
Start date
2020-12-07
Completion date
Unknown
Last updated
2021-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

blood conservation

Interventions

Group 1:Conventional AHHD
Group 2:Goal-oriented AHHD
Group 3:crystalloid fluid

Sponsors

Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-70 years; 2. ASAI- III 3. BMI 18.5-27.0 4. Hb >= 100g/L 5. Presumed blood loss exceeding 10% total blood volume.

Exclusion criteria

Exclusion criteria: 1. severe cardiovascular and cerebrovascular diseases; 2. preoperative renal insufficiency; 3. chronic obstructive pulmonary diseases; 4. coagulation disorders; 5. preoperative hepatic insufficiency; 6. emergency surgery; 7. preoperative infection; 8. current pregnancy.

Design outcomes

Primary

MeasureTime frame
Transfusion of blood products;—

Secondary

MeasureTime frame
complication;—

Countries

China

Contacts

Public ContactGuangmin Xu

Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital

xgmin2004@163.com+86 17708130256

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026