gastrointestinal dysmotility of Parkinson’ disease
Conditions
Interventions
PD group vs healthy control group:Nil
Sponsors
The Affiliated Suzhou Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age is not limited, men and women are not limited; 2. It meets Parkinson's diagnostic criteria, and at the same time, clear symptoms of constipation, while excluding organic disease, abnormal metabolism, abnormal brain structure, etc., and 2 specialists The attending or above-mentioned physicians make a joint diagnosis; 3. Stop all kinds of antibiotics, antifungal drugs, antiviral drugs, probiotics, prebiotics and immunosuppressive drugs, and other drugs that may affect the results of the study for more than 1 month; 4. Volunteer to participate in this experiment, the guardian signs the informed consent form, and can adhere to the treatment follow-up.
Exclusion criteria
Exclusion criteria: 1. Combined with other cardiovascular and metabolic diseases, such as hypertension, diabetes, hyperlipidemia, gout, coronary heart disease, etc. 2. Combined with other mental diseases. 3. Combined with other medical diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hoehn-Yahr (H-Y) grade;UPDRS;PAC-QOL score;Non-Motion Symptom Questionnaire (NMSS);SIBO;The average oral-cecal transit time(OCTT); | — |
Countries
China
Contacts
Public ContactKuai Xiao-Yi
The Affiliated Suzhou Hospital of Nanjing Medical University
Outcome results
None listed