Aortic stenosis
Conditions
Interventions
The experimental group:received ultrasound-guided iliac fascia block combined with MAC anesthesia
The control group:received MAC anesthesia only
Sponsors
General Hospital of the Northern Theater of the Chinese People's Liberation Army
Eligibility
Sex/Gender
All
Age
65 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1) New York Heart function grade III to IV; 2) Selective transcatheter aortic valve replacement; 3) Transcatheter cardiac surgery for the first time; 4) Informed consent has been signed.
Exclusion criteria
Exclusion criteria: 1) Emergency surgery; 2) Severe neurological symptoms such as stroke with sequelae; 3) Hemodynamic instability was defined as systolic blood pressure < 90mmHg; 4) Pulmonary disease with airway disorders, such as apnea syndrome; 5) Aortic balloon pump or ventricular assist device was placed before operation; 6) Severe liver and kidney dysfunction before operation (dialysis patients with chronic renal failure or chronic liver disease patients with child grade B or above); 7) Severe systemic infection; 8) There was infection at the nerve block site; 9) History of local anesthetic allergy; 10) Patients cannot cooperate with research, such as language understanding, mental illness, etc.; 11) Participated in other clinical trials within 3 months prior to inclusion in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative sufentanil use rate and total amount;Total use of propofol during operation;Respiratory depression related events: SpO2, nasopharynx airway implantation rate;Hemodynamic indexes: HR, BP, MAP;Usage rate and total amount of vasoactive drugs during operation;Usage rate and total amount of postoperative adjuvant analgesics;Postoperative pain score, patient and surgeon satisfaction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative ICU stay time;Incidence of adverse reactions (such as nausea / vomiting, puncture site infection / bleeding, delirium / stroke;Incidence of postoperative cardiac block;Incidence of acute kidney injury;Postoperative hospital stay;Incidence of severe cardiovascular and cerebrovascular events (MACCE) 30 days after operation;Incidence of chronic pain and its impact on daily life 30 days after operation;Incidence of neuropathic pain 30 days after operation;Readmission rate 30 days after operation;The mortality rate was 30 days after operation;One year mortality after operation; | — |
Countries
China
Contacts
Public ContactSun Yingjie
General Hospital of the Northern Theater of the Chinese People's Liberation Army
Outcome results
None listed