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Effects of hCG uterine perfusion on pregnancy outcomes in patients with endometrial immune abnormalities: a multicenter prospective study

Effects of hCG uterine perfusion on pregnancy outcomes in patients with endometrial immune abnormalities: a multicenter prospective study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000040873
Enrollment
Unknown
Registered
2020-12-12
Start date
2020-12-15
Completion date
Unknown
Last updated
2021-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometrial immune abnormality

Interventions

hCG group:hCG uterine perfusion
physiological saline group:physiological saline uterine perfusion

Sponsors

Shenzhen Zhongshan Urology Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1) Age less than 40 years; 2) Bilateral ovaries were intact without morphological abnormalities; 3) Both husband and wife have normal chromosomes; 4) The uterine cavity of the patient is normal, without adhesions or scars; 5) The patient's endocrine is normal; 6) No hydrosalpinx.

Exclusion criteria

Exclusion criteria: 1) History of hypertension, diabetes, ARTERiovenous thrombosis, liver disease, kidney disease, systemic lupus erythematosus, other autoimmune diseases; 2) For patients whose HCG injection date or before has been determined not to be suitable for fresh embryo transfer; 3) Have taken contraceptives or estrogen hormones in the past two months; 4) No other immunomodulatory drugs, including glucocorticoids and cyclosporin, were taken or perfused in the past two months.

Design outcomes

Primary

MeasureTime frame
Proportion of endometrial immune cells;Embryo implantation rate;Clinical pregnancy rate;abortion rate;ongoing pregnancy rate;

Countries

China

Contacts

Public ContactZeng Yong

Shenzhen Zhongshan Urology Hospital

zengyong1966@gmail.com+86 13008871163

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026