lung cancer
Conditions
Interventions
Gold Standard:Pathological diagnosis
Index test:GDNA 
detection 
 
analysis 
of 
epithelial 
cell 
samples,
Sponsors
he First Affiliated Hospital of Sun Yat-Sen University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1) Aged >= 18 years, regardless of gender. 2) A positive lung nodule is diagnosed by conventional chest CT or low-dose spiral CT (LDCT) and surgical resection is planned. In addition to the patients, three types of nodules (solid nodules, pure ground glass nodules, mixed ground glass nodules) can be included group, the size is 5~30mm. 3) Routine chest CT or LDCT scan was completed within 3 months before enrollment. 4) Willing to allow nasal mucosal epithelial cells, peripheral venous blood and surgically obtained pathological tissues according to the research protoco collection of biological samples such as FFPE. 5) The patient, guardian or close relatives can fully understand the informed consent form, agree to participate in the study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Pregnant or breastfeeding women. 2) Have received any blood transfusion within 30 days before surgery. 3) The patient had any malignant tumor (except non-melanoma skin cancer) that was clearly diagnosed by pathology within 5 years before enrollment (does not include cured cervical cancer or breast adenocarcinoma). 4) The patient, guardian or close relatives cannot understand or sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SEN, SPE, ACC, AUC of ROC; | — |
Countries
China
Contacts
Public ContactCheng Chao
The First Affiliated Hospital of Sun Yat-Sen University
Outcome results
None listed