A comparative study of the effects of dexmedetomidine and propofol on cardiac function in patients with sepsis

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000040821

Enrollment

Unknown

Registered

2020-12-11

Start date

2017-12-01

Completion date

Unknown

Last updated

2021-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spesis

Interventions

Dexmedetomidine Group:Dexmedetomidine

Propofol Group:Propofol

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: The patient was diagnosed on the international guidelines of severe sepsis and septic shock 2016, aged 18-74 years.

Exclusion criteria

Exclusion criteria: Pregnancy, past history of heart disease, such as: coronary heart disease, myocardial infarction, congenital heart disease, etc.; history of heart-related surgery, such as stent implantation, valve replacement, etc.; heart disease by other causes, such as chronic renal failure, hyperthyroidism, cirrhosis, COPD, etc..

Design outcomes

Primary

Measure	Time frame
cTnI;proBNP;EF;End-systolic inner diameter of left/right ventricle;End-diastolic diameter of left/right ventricle;	—

Countries

China

Contacts

Public ContactLiehua Deng

Department of Critical Care Medicine, Affiliated Hospital of Guangdong Medical University

glinson@126.com+86 13809752886

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026