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Relationship between serum mir-21 and mir-126 levels and reperfusion injury in patients with acute myocardial infarction

Value of mir-21-5p and mir-126 in predicting acute myocardial infarction

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000040803
Enrollment
Unknown
Registered
2020-12-10
Start date
2017-07-19
Completion date
Unknown
Last updated
2021-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Myocardial Infarction

Interventions

cholesterol&#32
(TC),&#32
low&#32
density&#32
blood&#32
pressure&#32
(SBP),&#32
diastolic&#32
(DBP),&#32
triglyceride&#32
(TG),&#32
total&#32
Gold Standard:Electrocardiogram, myocardial markers, coronary angiography
Index test:body&#32
mass&#32
index&#32
(BMI),&#32
systolic&#32

Sponsors

Shanxi Bethune Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Persistent chest pain of >= 30 min; significant ST segment elevation (>=0.1 mV or >=0.2 mV on >=2 adjacent limb or precordial leads, respectively, or new left bundle-branch block); onset of chest pain within 12 h; onset of chest pain more than 12 h accompanied by hemodynamic instability and hypovolemic shock.

Exclusion criteria

Exclusion criteria: Thrombolytic therapy for STEMI; valvular heart disease; myocarditis; cardiomyopathy; severe heart failure; severe liver and kidney dysfunction; hematological system diseases; malignant tumors; gastrectomy; acute and chronic infectious diseases; autoimmune diseases; bronchus asthma; abnormal calcium metabolism; thyroid or adrenal dysfunction; history surgery and trauma.

Design outcomes

Primary

MeasureTime frame
miR-21;miR-126;—

Countries

China

Contacts

Public ContactXuewen Li

Shanxi Bethune Hospital

xuewenli1010@126.com+86 13700504094

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026