A clinical study on perioperative pulmonary protection strategy for acute type A aortic dissection

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000040797

Enrollment

Unknown

Registered

2020-12-10

Start date

2017-11-30

Completion date

Unknown

Last updated

2021-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Type A Aortic Dissection

Interventions

Experience group 1:Urinastatin

Experience group 2:histidine-tryptophan-ketoglutarate solution

Experience group 3:Leukocyte depletion filter (artery)

Experience group 4:Leukocyte depletion filter (vein)

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: In accordance with the diagnostic and therapeutic guidelines for thoracic aortic disease (TAD) issued by ACC/AHA in 2010, patients with acute type A aortic dissection confirmed by clinical and imaging diagnosis and scheduled for emergency operation were enrolled in the group, aged 18-70 years, weighing 50-80 kg, and signed the informed consent.

Exclusion criteria

Exclusion criteria: Patients with a lot of pericardial effusion and pleural effusion before operation; patients with cardiopulmonary system diseases, nervous system diseases, blood system diseases, liver and kidney dysfunction, infection and thrombosis diseases; patients who had not signed the informed consent.

Design outcomes

Primary

Measure	Time frame
Oxygenation index;Plasma inflammatory factors;	—

Countries

China

Contacts

Public ContactZHU Junming

Beijing Anzhen Hospital, Capital Medical University

anzhenzjm@163.com+86 13801132276

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026