general anesthesia
Conditions
Interventions
Group M:propofol TCI
Group C1:propofol closed-loop TCI,BIS 55
Group C2:propofol closed-loop TCI,BIS 50
Group C3:propofol closed-loop TCI,BIS 45
Sponsors
Plastic Surgery hospital(institute), CAMS, PUMC
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. general anesthesia should be selected for selective operation and operation time >60min; 2. ASA grade I or II; 3. aged 18-50 years old; 4. BMI<30kg/m2; 5. Understand the informed consent and agree to sign the informed consent before the study.
Exclusion criteria
Exclusion criteria: 1. overstrain; 2. the cardiovascular, respiratory, neurological and endocrine system diseases; 3. the abnormal function of the liver and kidney; 4. the drug history of alcohol dependence; 5. the abnormal airway; 6. the hearing, intelligence and communication barriers; 7. patients can not use BIS electrode in the forehead.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BIS;blood pressure;percetage of BIS time in the property interval;Propofol plasma target concentration;Regulation of the target concentration of propofol;awake time;total amount of propofol;Controlled Hypotensive Drugs;satisfaction of doctor and patient; | — |
Countries
China
Contacts
Public ContactWenli XU
Plastic Surgery hospital(institute), CAMS, PUMC
Outcome results
None listed