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Effect of oral administration of esketamine on sedation and venipuncture analgesia for premedication in children

Effect of oral administration of esketamine on sedation and venipuncture analgesia for premedication in children

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000040739
Enrollment
Unknown
Registered
2020-12-08
Start date
2020-12-14
Completion date
Unknown
Last updated
2021-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preoperative medication for children

Interventions

BC:3ml 10% dextrose water
EK1:Add 1mg/kg of esketamine with 10% glucose water to 3ml
EK2:Add 2mg/kg of esketamine with 10% glucose water to 3ml

Sponsors

Liaocheng People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Children undergoing elective surgery in otolaryngology department of Liaocheng People's Hospital from December 2020 to May 2021 were included. The children were 1 to 6 years old, with ASA grade 1 to 2, and there was no history of congenital heredity or mental retardation.

Exclusion criteria

Exclusion criteria: Preoperative evaluation of patients with difficult airway, with a history of upper respiratory tract infection within one week.

Design outcomes

Primary

MeasureTime frame
Acceptance of oral medication in children;Mother and child separation score;Acceptance rate of mother and child separation;Venipuncture score;Acceptance rate of venipuncture;

Secondary

MeasureTime frame
Sedation and emotional state scores at 5, 10, 15, 20, 25, 30 minutes after administration;Onset time, mother-child separation time, venipuncture time,;

Contacts

Public ContactZunyuan Liu

Liaocheng People's Hospital

ly29.love@163.com+86 18263511977

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026