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Significance of the dissection of lymph nodes at the root of middle artery of the colon(No.223) with tumors near the splenic flexure of the transverse colon and the splenic flexure of the colon : a multicentre prospective controlled study

Significance of the dissection of lymph nodes at the root of middle artery of the colon(No.223) with tumors near the splenic flexure of the transverse colon and the splenic flexure of the colon: a multicentre prospective controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000040733
Enrollment
Unknown
Registered
2020-12-08
Start date
2020-12-06
Completion date
Unknown
Last updated
2021-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colon cancer

Interventions

Intervention Group:Routine lymph node dissection + No.233 lymph node dissection

Sponsors

The First Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Patients voluntarily participate in and sign the informed consent; (2) Male or non-pregnant female patients aged 18-75 years; (3) the American society of anesthesiologists ASA I to III; (4) The patient does not have other malignant diseases; (5) The patient did not receive other anti-tumor treatment before surgery; (6) II / III transverse colon nearly splenic flexure and splenic flexure colon cancer patients (standard in 2010, according to AJCC staging seventh edition, see appendix a); (7) The surgical method was determined as radical resection of the left colon cancer (CME); (8) Pathological diagnosis was colorectal adenocarcinoma or mucinous carcinoma; (9) Consent to receive supplementary treatment in accordance with the standard.

Exclusion criteria

Exclusion criteria: (1) serious cardiovascular, respiratory, kidney, liver disease or diabetes; (2) Mental disorders or diseases; (3) Pregnant or lactating women; (4) Contraindications to chemotherapy; (5) Preoperative staging was considered as cT1N0 or cT4bNany; (6) Patients with distant metastasis and tumor invasion of surrounding organs require combined resection of organs or cannot achieve R0 resection; (7) Previous history of malignant tumor or complex major abdominal surgery; (8) Patients with intestinal obstruction, intestinal perforation, intestinal bleeding and other conditions requiring emergency surgery; (9) Poor patient compliance or poor patient compliance considered by the researcher; (10) Refusal to sign the informed consent; (11) Patients with other clinical and laboratory conditions considered by the researcher as unfit to participate in the trial.

Design outcomes

Primary

MeasureTime frame
Postoperative 5-year recurrence-free survival;

Secondary

MeasureTime frame
Postoperative 3-year recurrence-free survival;Postoperative 3- and 5-year overall survival;Postoperative complications and 30-day mortality;

Countries

China

Contacts

Public ContactSong Wu

The First Affiliated Hospital of Sun Yat-sen University

songwu@mail.sysu.edu.cn+86 13824444536

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026