Colon cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Patients voluntarily participate in and sign the informed consent; (2) Male or non-pregnant female patients aged 18-75 years; (3) the American society of anesthesiologists ASA I to III; (4) The patient does not have other malignant diseases; (5) The patient did not receive other anti-tumor treatment before surgery; (6) II / III transverse colon nearly splenic flexure and splenic flexure colon cancer patients (standard in 2010, according to AJCC staging seventh edition, see appendix a); (7) The surgical method was determined as radical resection of the left colon cancer (CME); (8) Pathological diagnosis was colorectal adenocarcinoma or mucinous carcinoma; (9) Consent to receive supplementary treatment in accordance with the standard.
Exclusion criteria
Exclusion criteria: (1) serious cardiovascular, respiratory, kidney, liver disease or diabetes; (2) Mental disorders or diseases; (3) Pregnant or lactating women; (4) Contraindications to chemotherapy; (5) Preoperative staging was considered as cT1N0 or cT4bNany; (6) Patients with distant metastasis and tumor invasion of surrounding organs require combined resection of organs or cannot achieve R0 resection; (7) Previous history of malignant tumor or complex major abdominal surgery; (8) Patients with intestinal obstruction, intestinal perforation, intestinal bleeding and other conditions requiring emergency surgery; (9) Poor patient compliance or poor patient compliance considered by the researcher; (10) Refusal to sign the informed consent; (11) Patients with other clinical and laboratory conditions considered by the researcher as unfit to participate in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative 5-year recurrence-free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative 3-year recurrence-free survival;Postoperative 3- and 5-year overall survival;Postoperative complications and 30-day mortality; | — |
Countries
China
Contacts
The First Affiliated Hospital of Sun Yat-sen University