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Factors associated with the occurrence and prognosis of post-stroke seizures/epilepsy

A long-term follow-up cohort study on the occurrence and treatment outcomes of post-stroke seizures/epilepsy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000040725
Enrollment
Unknown
Registered
2020-12-08
Start date
2021-01-01
Completion date
Unknown
Last updated
2021-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-stroke seizures

Interventions

patients with early-onset post-stroke seizure:Levatiracetam
patients with early-onset post-stroke seizure:Lamotrigine
patients with early-onset post-stroke seizure:Oxcarbazepine
patients with late-onset post-stroke seizure:Levatiracetam
patients with late-onset post-stroke seizure:Lamotrigine
patients with late-onset post-stroke seizure:Oxcarbazepine
patients with late-onset post-stroke seizure:Depakine
patients with early-onset post-stroke seizure:Depakine

Sponsors

Department of Neurology, the First Affiliated Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients with recurrent or late-onset epilepsy after stroke; 2. Onset age >=18 years.

Exclusion criteria

Exclusion criteria: (1) patients with a prior diagnosis of epilepsy; (2) patients with secondary ICH or venous infarction; (3) patients whose seizure might be attributed to other potential causes (e.g., brain tumor, intracranial vascular malformation, traumatic brain injury); (4) patients who cannot be completed effectiveness/safety assessment at least for one time; (5) patients who cannot cooperate with recording the seizures or have difficulty to record seizures; (6) patients who disagree to join this study.

Design outcomes

Primary

MeasureTime frame
time to seizure recurrence;NIHSS Score;mRS Score;

Secondary

MeasureTime frame
MMSE??;Moca score;the incidence of refractory epilepsy;HAMA score;HAMD Score;Responder rate of anti-epileptic treatment;The incidence rate of adverse events;seizure-free rate;Mortality;radiomics data;

Countries

China

Contacts

Public ContactXinshi Wang

the First Affiliated Hospital of Wenzhou Medical University

wangxinshi@wmu.edu.cn+86 13757897051

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026