Effect of quadratus lumborum block on cognitive function in elderly patients with hip fracture

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Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000040724

Enrollment

Unknown

Registered

2020-12-08

Start date

2021-01-01

Completion date

Unknown

Last updated

2021-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

PND

Interventions

experimental group:QLB

control group:none

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged >=65 years old; 2. American Society of Anesthesiologists (ASA) classification I ~ II; 3. Elective hip replacement surgery; 4. Have received primary school education or above; 5. Preoperative simple Mental State Scale (MMSE) score >=24 points.

Exclusion criteria

Exclusion criteria: 1. Severe visual and auditory disorders; 2. Unable to cooperate with the completion of the test; 3. Serious heart, lung, brain, liver and kidney diseases; 4. There were mental illness and cognitive impairment before operation; 5. A history of substance abuse or drug addiction; 6. History of local anesthetic allergy; 7. Puncture site infection.

Design outcomes

Primary

Measure	Time frame
PND;	—

Secondary

Measure	Time frame
VAS;sufentanil dosage 24h after surgery;HMGB1;IL-6;	—

Contacts

Public ContactZhu Manhua

Ningbo Medical Center Lihuili Hospital

jszhumanhua@163.com+86 18868658089

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 7, 2026