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Effect of lung recruitment combined with individualized PEEP on pulmonary function in elderly patients undergoing laparoscopic radical prostatectomy

Effect of lung recruitment combined with individualized PEEP on pulmonary function in elderly patients undergoing laparoscopic radical prostatectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000040722
Enrollment
Unknown
Registered
2020-12-08
Start date
2020-12-07
Completion date
Unknown
Last updated
2021-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung protection strategy in laparoscopic radical prostatectomy

Interventions

lung recruitment +PEEP 5cmH2O:lung recruitment combined with PEEP 5cmH2O
lung recruitment + individualized PEEP:lung recruitment combined with individualized PEEP

Sponsors

Department of Anesthesiology, First Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1. Patients who are ranged from 65 to 80 years old; 2. BMI 19~28kg/m2,ASA grade II to III; 3. undergo elective laparoscopic radical prostatectomy under general anesthesia; 4. no complications about severe cardiopulmonary; 5. cerebrovascular; 6. The patients had not undergone surgery and had not undergone thoracic surgery in past 4 weeks.

Exclusion criteria

Exclusion criteria: 1. The ventilation strategy can not maintain oxygenation (SpO240cmH2O; 5. change to laparotomy.

Design outcomes

Primary

MeasureTime frame
Blood gas analysis;inflammatory factors CC16, SP-D, TNF-alpha;—

Secondary

MeasureTime frame
DP (Pplat – PEEP); Vd/Vt (PaCO2-PETCO2) / PaCO2); OI (FiO2 / PaO2);Vital signs (BP, HR, SPO2, ETCO2);Incidence of postoperative atelectasis;Pulmonary complications;—

Countries

China

Contacts

Public ContactFuhai Ji

The First Affiliated Hospital of Soochow University

jifuhai@suda.edu.cn+86 13656207331

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026