Infant outcomes following treatment of prenatal stress by mindfulness intervention: a randomized controlled trial

Mechanism study of maternal prenatal stress on offspring’s neuropsychological maldevelopment mediated by infant intestinal microbiota

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000040717

Enrollment

Unknown

Registered

2020-12-08

Start date

2020-12-10

Completion date

Unknown

Last updated

2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pregnant women

Interventions

Intervention group:mindfulness intervention

control group:Routine care

Eligibility

Sex/Gender

Female

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: aged 18 years and over; in the 12th to 20th week of gestation; Edinburgh Postnatal Depression Scale (EPDS) scores >=9 or Generalized Anxiety Disorder 7-item Scale (GAD-7) scores >=5; single pregnancy; fluent in Chinese; not part of or on the waiting list of another psychological intervention; able to use application on Wechat for the study

Exclusion criteria

Exclusion criteria: presence of suicidal ideation (score >=1 on item 10 of the EPDS);severe mental disorders (e.g., a diagnosis of psychotic disorders) or physical diseases (e.g., cancer, cardiocerebrovascular diseases); drug abuse or dependence; prior mindfulness experience

Design outcomes

Primary

Measure	Time frame
prenatal distress;	—

Secondary

Measure	Time frame
infant development;	—

Countries

China

Contacts

Public ContactCao Fenglin

School of Nursing and Rehabilitation, Shandong University

caofenglin2008@126.com+86 531 88382291

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 10, 2026