prostate cancer
Conditions
Interventions
csPCa:transrectal ultrasound-guided systematic prostate biopsy
without csPCa:transrectal ultrasound-guided systematic prostate biopsy
Sponsors
Department of Urology, ShengJing Hospital of China Medical University
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: The inclusion criteria were as follows: men aged > 18 years who underwent consecutive TRUS-guided systematic prostate biopsy, had negative biparametric MRI (bpMRI, score < 3 points evaluated by PI-RADS 2.0) results, negative transrectal ultrasound (no hypoechoic nodules in the peripheral zone), and negative digital rectal examination. Men with a PSA level <=30 ng/ml (to allow interpretation of results more relevant to a screening-based population) were recruited. Studies included both biopsy-na?ve men and those with a prior negative biopsy. The interval between MRI and biopsy was < 3 months.
Exclusion criteria
Exclusion criteria: The exclusion criteria were as follows: patients with prior prostate cancer, surgical treatment for benign prostate hyperplasia (BPH), no MRI data due to contraindications (metal implants, etc.), evidence of acute urinary tract infections, acute prostatitis, and patients taking a 5a-reductase inhibitor or anti-androgen at the time of biopsy or during the previous 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PSAD;demographic and history datd; | — |
Countries
China
Contacts
Public ContactSong Bai
Department of Urology, ShengJing Hospital of China Medical University
Outcome results
None listed