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The differentiation of human bone marrow mesenchymal stem cells induced by human book-shaped acellular three-phase scaffold and its mechanism for promoting the repair of bone?tendon healing

The differentiation of human bone marrow mesenchymal stem cells induced by human book-shaped acellular three-phase scaffold and its mechanism for promoting the repair of bone?tendon healing

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000040660
Enrollment
Unknown
Registered
2020-12-07
Start date
2020-12-04
Completion date
Unknown
Last updated
2021-03-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sport injury

Interventions

Two groups:human book-shaped acellular three-phase scaffold

Sponsors

Xiangya Hospital, Central South University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Aged 18-70 years old; (2) The sample donor has undergone thigh amputation in our hospital; (3) Sample donors agree to donate part of the surgical samples for this study; (4) Obtain the sample donor's informed consent.

Exclusion criteria

Exclusion criteria: (1) Infectious diseases such as hepatitis B, tuberculosis, HIV infection; (2)With metabolic diseases such as diabetes mellitus, hyperthyroidism, etc.; (3) Complicated with long-term chronic organic diseases such as chronic obstructive pulmonary disease, cardiac insufficiency; (4) combined with malignant tumor; (5) Combined with local degenerative diseases such as osteoarthritis (6) Previous long bed history; (7) Combined operation contraindications such as liver and kidney failure, severe anemia, coagulation dysfunction, etc.

Design outcomes

Primary

MeasureTime frame
histology;—

Countries

China

Contacts

Public ContactShi Qiang

Department of Sports Medicine, Xiangya Hospital, Central South University

shiqiang2018@csu.edu.cn+86 18229861249

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026