Multimodal MRI, as an objective marker of efficacy, pre- and post navigation rTMS treatment in patients with depression

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000040616

Enrollment

Unknown

Registered

2020-12-03

Start date

2016-12-01

Completion date

Unknown

Last updated

2021-03-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

depression

Interventions

control group:Transcranial magnetic stimulation on the dorsolateral frontal lobe

experimental group:Transcranial magnetic stimulation on motor cortex

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. The diagnostic criteria for major depressive episode of dsm-v were met through the standardized interview evaluation; 2. They are between 18 and 65 years old; 3. The score of the 17-item version of Hamilton depression scale is above 18.

Exclusion criteria

Exclusion criteria: 1. Presence of other serious mental and physical disorders; 2. Unable to pass the security check of TMS; 3. Use benzodiazepines; 4. Unable to pass the security screening of MRI.

Design outcomes

Primary

Measure	Time frame
Hamilton's Depression Scale;	—

Secondary

Measure	Time frame
Beck depression self-rating scale;functional magnetic resonance imaging;	—

Countries

China

Contacts

Public ContactGeorg Northoff

Hangzhou Seventh People's Hospital

Georg.Northoff@theroyal.ca+86 15158114739

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026