Study on the brain mechanism of action observation training and sensory observation training in healthy population and stroke patients

The effects of action observation training and sensory observation training based on mirror neurons and embodied perception on upper limb function after stroke and its brain mechanism

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000040609

Enrollment

Unknown

Registered

2020-12-03

Start date

2020-12-09

Completion date

Unknown

Last updated

2021-03-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Group A:none

Group B:routine rehabilitation

Eligibility

Sex/Gender

All

Age

30 Years to 75 Years

Inclusion criteria

Inclusion criteria: Stroke Patients (1)Patients with unilateral cerebral hemorrhage or cerebral infarction confirmed by CT or MRI and diagnosed the relevant criteria of Chinese Guidelines for Diagnosis and Treatment of Acute Ischemic Stroke 2018; (2) First stroke or previous lacunar cerebral infarction with motor dysfunction of upper limbs (Brunnstrom grade II-V); (3) Aged 30 to 75 years old; men and women; (4) Right-handedness; primary school and above education level; (5) No aphasia (WAB > 93.8), normal language function before onset; (6) No cognitive dysfunction (MMES > 17); (7) Sign informed Consent. Healthy Subjects (1) Aged 30 to 75 years old; men and women; (2) Right-handedness; primary school and above education level; (3) Without any special past medical history; (4) Without any pathological clinical symptoms or pathological changes judged by imaging. (5) Sign informed Consent.

Exclusion criteria

Exclusion criteria: (1) With serious primary or secondary diseases, such as severe liver and kidney hematopoietic system diseases, severe cardiopulmonary insufficiency or infectious diseases; (2) Any other medical condition or history that affects motor function; (3) Pregnant or lactating women; (4) Persons addicted to drugs, alcohol or other substances; (5) Skull defects, pacemakers and metal implants are not suitable for MRI and TMS examination.

Design outcomes

Primary

Measure	Time frame
MRI mutlimodal image data;Fugl-Meyer Upper Extremity Motor Assessment Scale;	—

Secondary

Measure	Time frame
Functional near-infrared spectroscopy;Transcranial magnetic stimulation;Electroencephalogram;Brunnstrom;Modified Ashworth Scale;Box and Block Test;Modified Barthel Index, MBI;Sensory of upper limb;Muscle strength of upper limb;	—

Countries

China

Contacts

Public ContactChunlei Shan

Shanghai University of Traditional Chinese Medicine

shanclhappy@163.com+86 18616974986

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026