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Status, Influencing Factors and Intervention Effects of Sudden Unexpected Postnatal in China: A Multi-center Trial

Status, Influencing Factors and Intervention Effects of Sudden Unexpected Postnatal in China: A Multi-center Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000040600
Enrollment
Unknown
Registered
2020-12-03
Start date
2021-01-01
Completion date
Unknown
Last updated
2021-03-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sudden unexpected postnatal collapse/sudden death in newborn

Interventions

Intervention group:implement surveillance programs during the hospital stay
Intervention group:implement RAPPT risk scoring system

Sponsors

Children's Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. premature or term infants admitted to the NICU of each hospital during the study, <35 weeks of gestational age; <=28 days of age, diagnosed with sudden unexpected postnatal collapse (SUPC) or sudden death in newborn(SDN); 2. Sudden unexpected postnatal collapse occurs in term or near-term newborns who are healthy at birth, have 5-minute Apgar scores of 8 or more, and then experience cardiorespiratory collapse within the first week of life; 3. SDN refers to apparent life-threatening events occur in healthy or stable or "slight" newborns, who are suddenly pale, loss of consciousness, respiratory arrest, hypotonic, cyanosis, died after resuscitation.

Exclusion criteria

Exclusion criteria: Premature infants with gestational age <35 weeks; Apgar score < 8 at 5 or 10 minutes; Neonatal death due to violent trauma; Have birth defects.

Design outcomes

Primary

MeasureTime frame
Blood gas;Amplitude integrated EEG;cranial sonography;cranial MRI;CSF culture;CSF routine;biochemical analysis of CSF;Morphological analysis of CSF cell;Developmental Screening Test for Child under six (DST);Neonatal Behaviral Neurological Assessment, NBNA;Bayley scales of infant development, BSID;mental development index, MDI;psychomotor development index, PDI;

Countries

China

Contacts

Public ContactZhou Xiaoguang

Children's Hospital of Nanjing Medical University

gzzhouxg@163.com+86 18951769771

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026