Application of different approaches of ultrasound-guided posterior quadratus lumborum block in laparoscopic radical gastrectomy for gastric cancer

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000040587

Enrollment

Unknown

Registered

2020-12-03

Start date

2020-12-01

Completion date

Unknown

Last updated

2021-03-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastric carcinoma

Interventions

Q1 group:QLB1 approach

Q2 group:QLB2 approach

Q3 group:QLB3 approach

Q4 group:QLB4 approach

C group:Blank control

Eligibility

Sex/Gender

All

Age

20 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 20 to 75 years old; 2. Elective laparoscopic radical gastrectomy for gastric cancer; 3. BMI1 8 to 35; 4. ASA I~III; 5. Agree to receive ultrasound-guided quadratus lumbar nerve block and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with severe heart, lung, brain, liver, kidney and other basic diseases; 2. Patients with contraindications for nerve block; 3. Patients with cognitive impairment and unable to complete data collection; 4. Recent use of sedatives or analgesics; 5. Patients allergic to local anesthetics; 6. Patients with previous abdominal operation history or conversion to open surgery; 7. Preoperative long-term poor glycemic control / diabetic patients; 8. Patients with metabolic disorders associated with increased / decreased cortisol.

Design outcomes

Primary

Measure	Time frame
VAS scores at 0, 6, 12, 24 and 48 hours after operation;Preoperative blood glucose, cortisol, T cell subsets (CD3 +, CD4 +, CD8 +) levels;Blood glucose, cortisol and T cell subsets (CD3 +, CD4 +, CD8 +)levels were measured at 0, 12, 24 and 48 hours after operation;Time of first exhaust after operation;The first time to get out of bed after operation;Time of first fluid diet after operation;PCIA press times after operation;Total use of remedial analgesics;Total use of opioids in perioperative period;	—

Measure

Time frame

VAS scores at 0, 6, 12, 24 and 48 hours after operation;Preoperative blood glucose, cortisol, T cell subsets (CD3 +, CD4 +, CD8 +) levels;Blood glucose, cortisol and T cell subsets (CD3 +, CD4 +, CD8 +)levels were measured at 0, 12, 24 and 48 hours after operation;Time of first exhaust after operation;The first time to get out of bed after operation;Time of first fluid diet after operation;PCIA press times after operation;Total use of remedial analgesics;Total use of opioids in perioperative period;

—

Secondary

Measure	Time frame
Hemodynamic changes before and after skin incision (MBP, HR);Onset time and range of posterior quadratus lumborum block;Postoperative adverse reactions;	—

Countries

China

Contacts

Public ContactChange Feng

Second Hospital of Shandong University

fengchang@sdu.edu.cn+86 17660085521

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026