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Comparison of the efficacy of sulfonda heparin sodium and low molecular weight heparin calcium in preventing thrombosis in patients with lower extremity fractures

Comparison of the efficacy of sulfonda heparin sodium and low molecular weight heparin calcium in preventing thrombosis in patients with lower extremity fractures

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000040575
Enrollment
Unknown
Registered
2020-12-03
Start date
2020-12-31
Completion date
Unknown
Last updated
2021-03-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Deep venous thrombosis (DVT) occurs in lower extremity fractures

Interventions

A:Sulfonda heparan sodium
B:Low molecular weight heparin calcium

Sponsors

Chengdu Shuangliu District First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1) the proposed line of orthopedic ? for lower limb surgery and incision of patients; 2) aged 18 to 70 years old; 3) Male or female; 4) The patient agrees to participate in the trial and signs the informed consent; 5) Preoperative examination showed no thrombosis.

Exclusion criteria

Exclusion criteria: 1) Patients with systemic chronic wasting diseases such as hyperthyroidism, diabetes, and malignant tumors; 2) Patients with vasculogenic diseases or skin diseases such as vasculitis, varicose veins, deep venous thrombosis and psoriasis at the surgical site; 3) Patients with local or systemic infection; 4) Persons with scar constitution; 5) Long-term use of immunosuppressants, cytoinhibitors, hormone anticoagulants and other drugs; 6) Patients with previous surgical history in the surgical area; 7) Patients with connective tissue diseases such as rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE); 8) Severe liver and kidney dysfunction, cardiovascular and cerebrovascular diseases; 9) those suffering from neuropsychiatric diseases and unable to cooperate with the treatment; 10) Abnormal coagulation function; 11) The presence of other diseases or conditions known to affect wound healing.

Design outcomes

Primary

MeasureTime frame
Incidence of venous thrombosis of lower extremities;Incidence of pulmonary thromboembolism;

Countries

China

Contacts

Public ContactHai-bo Li

Chengdu Shuangliu District First People's Hospital

haibo1964@163.com+86 13666298396

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026