melanoma
Conditions
Interventions
Gold Standard:immunohistochemical pathology of lymph nodes
Index test:A 
co-axial 
projection 
system 
for 
melanoma 
lymph 
Sponsors
The First Affiliated Hospital of University of Science and Technology of China
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) The clinical stage of the patient is T1 and T2 cutaneous melanoma; the primary lesions of the patient are confirmed by the pathological diagnosis as primary skin malignant melanoma; (2) After the clinical physical examination by more than 2 doctors before the operation, no signs of clinical metastasis were found in the regional lymph nodes; (3) The patient will receive at least one imaging evaluation, such as Doppler ultrasound, enhanced CT, enhanced magnetic resonance imaging (MRI) and PET/CT, etc., to confirm that there are no signs of distant metastasis and regional lymph node metastasis, and some highly suspicious patients require puncture cytology to exclude metastases.
Exclusion criteria
Exclusion criteria: (1) Iodine/ICG allergy patients; (2) Pregnancy; (3) Patient with a skin disease who cannot receive laser irradiation; (4) Patient who undergoes an assessment of the overall condition before surgery confirms that he/she cannot tolerate extensive resection of the primary tumor, sentinel biopsy of regional lymph nodes, regional lymph node dissection, and the corresponding anesthesia; (5) Patients who have an adverse reaction and terminate the treatment are not included in the curative effect but included in the incidence of adverse reactions.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of sentinel lymph nodes with fluorescence;Location of sentinel lymph node with fluorescence;Sentinel node detection rate;False negative rate of sentinel lymph node;SEN, SPE, ACC, AUC of ROC; | — |
Countries
China
Contacts
Public ContactLiping Zhao
The First Affiliated Hospital of University of Science and Technology of China
Outcome results
None listed