The effects of action observation training and sensory observation training based on mirror neurons and embodied perception on upper limb function after stroke and its brain mechanism

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000040568

Enrollment

Unknown

Registered

2020-12-02

Start date

2020-12-07

Completion date

Unknown

Last updated

2021-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Group A:routine rehabilitation + action observation training

Group B:routine rehabilitation+action observation training + sensory stimulation therapy

Group C:routine rehabilitation+action observation training + sensory observation training

Eligibility

Sex/Gender

All

Age

30 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Patients with unilateral cerebral hemorrhage or cerebral infarction confirmed by CT or MRI and diagnosed the relevant criteria of Chinese Guidelines for Diagnosis and Treatment of Acute Ischemic Stroke 2018; (2) First stroke or previous lacunar cerebral infarction with motor dysfunction of upper limbs(Brunnstrom grade II-V); (3) Aged 30 to 75 years old; men and women; (4) Right-handedness;primary school and above education level; (5) No aphasia (WAB > 93.8), normal language function before onset; (6) No cognitive dysfunction (MMES > 17); (7) Sign informed Consent.

Exclusion criteria

Exclusion criteria: (1) With serious primary or secondary diseases, such as severe liver and kidney hematopoietic system diseases, severe cardiopulmonary insufficiency or infectious diseases; (2) Any other medical condition or history that affects motor function; (3) Pregnant or lactating women; (4) Persons addicted to drugs, alcohol or other substances; (5) Skull defects, pacemakers and metal implants are not suitable for MRI and TMS examination.

Design outcomes

Primary

Measure	Time frame
Fugl-Meyer Upper Extremity Motor Assessment Scale;MRI mutlimodal image data;	—

Secondary

Measure	Time frame
Brunnstrom;Modified Ashworth Scale;Box and Block Test;Modified Barthel Index, MBI;Muscle strength of upper limb;Sensory of upper limb;Functional near-infrared spectroscopy;Transcranial magnetic stimulation;	—

Countries

China

Contacts

Public ContactChunlei Shan

Shanghai University of Traditional Chinese Medicine

shanclhappy@163.com+86 18616974986

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 9, 2026