Efficacy and safety of dexamethasone during the perioperative period of total hip arthroplasty

Efficacy and safety of two doses of dexamethasone for total hip arthroplasty during perioperative period

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000040560

Enrollment

Unknown

Registered

2020-12-02

Start date

2020-12-10

Completion date

Unknown

Last updated

2021-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

orthopedic surgery

Interventions

Group A:dexamethasone before surgery and 24h later

Group B:dexamethasone before surgery and 24h,48h later

Group C:based on groupB,combined with aggressive warming

Eligibility

Sex/Gender

Male

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) patients received unilateral THA; (2) Understand and sign the informed consent.

Exclusion criteria

Exclusion criteria: (1) allergy to Dexa; (2) Age =75 years; (3) any glucocorticoids within 3 months before surgery or any strong opioids within 1 week; (4) history of severe heart disease (NYHA>=3), liver and kidney failure, systemic rheumatic diseases (rheumatoid arthritis, ankylosing spondylitis, systemic lupus erythematosus); (5) ipilateral hip surgery history; (6) without normal cognitive function and sensation; (7) lost to follow-up.

Design outcomes

Primary

Measure	Time frame
Pain;	—

Countries

China

Contacts

Public ContactLi Fulin

Guangxi Zhuang Autonomous Region People's Hospital

709184237@qq.com+86 18276501990

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 9, 2026