The effect of different doses alfentanil and dexmedetomidine on prevention of emergency agitation in pediatric tonsillectomy and adenoidectomy surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000040530

Enrollment

Unknown

Registered

2020-12-01

Start date

2020-12-01

Completion date

Unknown

Last updated

2021-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tonsil hhypertrophy

Interventions

control group:saline

Dex group:Dexmedetomidine 0.4ug/kg

Dex+Alf1 group:dexmedetomidine 0.4ug/kg+Alfentanil10ug/kg

Dex+Alf2 group:dexmedetomidine 0.4ug/kg+Alfentanil20ug/kg

Eligibility

Sex/Gender

All

Age

3 Years to 7 Years

Inclusion criteria

Inclusion criteria: (1) Patients with definite indications of palatopharyngeal tonsillectomy; (2) Children aged 3-7 years; his or her guardian want his or her child participate in this study voluntarily and signing the informed consent; (3) Repeated tonsil infection, tonsil enlargement of more than 2 degrees, snoring; (4) ASA Level I-II.

Exclusion criteria

Exclusion criteria: (1) Heart disease; (2) Developmental delay; (3) Abnormal upper respiratory tract; (4) asthma; (5) Obstructive sleep apnea syndrome (OSAS); (6) Patients with a history of upper respiratory tract infection within 4 weeks; (7) Refuse to participate in the experimenter.

Design outcomes

Primary

Measure	Time frame
Aono‘s scale;	—

Secondary

Measure	Time frame
FLACC Scale;awake time;	—

Countries

China

Contacts

Public ContactZhang Yanzhuo

Liuzhou Workers Hospital

zhangyanzhuo625@sina.com+86 17745126625

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026