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Clinical Study of Guangsi Yulin Decoction's Effect on Sperm DNA Fragmentation Index of asthenospermia patients

Clinical Study of Guangsi Yulin Decoction's Effect on Sperm DNA Fragmentation Index of asthenospermia patients

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000040516
Enrollment
Unknown
Registered
2020-12-01
Start date
2020-12-01
Completion date
Unknown
Last updated
2021-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Asthenospermia

Interventions

Sponsors

Dongzhimen Hospital, Beijing University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
22 Years to 45 Years

Inclusion criteria

Inclusion criteria: (1) Meet the western medical diagnostic criteria of "male infertility" and "asthenospermia", and have the two diagnoses at the same time; (2) TCM syndrome differentiation conforms to kidney deficiency syndrome; (3) Male aged 22 to 45 years; (4) Married, husband and wife have a harmonious family relationship; (5) Sperm DNA fragmentation index (DFI) >=30%; (6) No other organic lesions of the reproductive system; (7) Those who did not receive treatment with similar drugs or other therapies within 2 weeks before the study; (8) Understand the content of the study and sign the informed consent. Those who meet the above 8 criteria at the same time will be included in the study; otherwise, they will not be included

Exclusion criteria

Exclusion criteria: (1) According to the Manual of Human Semen Examination and Treatment Laboratory, edition 5, except for total sperm motility < 40% and forward motility < 32%, there are other abnormalities in semen examination; (2) Patients with a family history of genetic diseases; (3) Suffering from varicocele, prostatitis and other diseases that lead to sperm quality decline; (4) Patients with active infection; (5) Patients with severe primary diseases such as cardiovascular, liver, kidney and hematopoietic system; (6) Patients with mental disorders; (7) Patients who have a long-term and large amount of smoking and drinking habits, or are exposed to high temperature, radiation and toxic chemical environment, but cannot change or give up; (8) Allergic constitution and allergic to multiple drugs. Meeting any of the above is considered as meeting the exclusion criteria, and exclusion is required.Those who meet the above 8 criteria at the same time will be included in the study; otherwise, they will not be included

Design outcomes

Primary

MeasureTime frame
Semen routine;

Countries

China

Contacts

Public ContactHai-Song Li

Dongzhimen Hospital, Beijing University of Chinese Medicine

lihs369@sina.com+86 13601221399

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026