joint and spine diseases
Conditions
Interventions
Case series:surgical treatment with personalized implants
Sponsors
Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Participants aged 18-75 years; 2. Participants who need to undergo osteoarticle-spine reconstructive surgery for various osteoarticle-spine diseases (degenerative diseases of the lumbar spine, tuberculosis of the lumbar spine, tumors, infections and acetabular defects, etc.); 3. Did not participate in any other clinical trials within 3 months; 4. Did not undergo any spinal or joint related surgery within 6 months; 5. There is no improvement in the non-surgical treatment that has been performed for more than 3 months in the past year, and the existing commercial implants cannot meet the surgical needs; 6. Can understand the research program, participate in the study voluntarily, and sign the informed consent; 7. Willing to complete the experimental follow-up and data collection during the study.
Exclusion criteria
Exclusion criteria: 1. Participants unwilling to accept personalized reconstructive surgery; 2. Participants unable to tolerate anesthesia due to physical conditions; 3. Participants with severe osteoporosis (T <=-2.5 and complicated with brittle fracture); 4. Participants with tissue metabolism disorder, immune function disorder, drug abuse, etc.; 5. Participants with heart, lung, liver, kidney hematopoietic system, endocrine system and other serious primary diseases or mental diseases; 6. Allergic to metal or titanium alloy materials, allergic constitution or allergic to multiple drugs; 7. Pregnant and lactating women; 8. Participants are unwilling or unable to restrict activities or comply with the will; 9. The condition is critical, affecting the evaluation of the effectiveness and safety of the test apparatus.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fusion stability; | — |
Countries
China
Contacts
Public ContactZhao Jie
Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed