Rectal cancer
Conditions
Interventions
Preoperative Preparation group (experimental group):endoluminal draining after surgery
Preoperative Preparation group (experimental group):digital anal dilatation
Preoperative Preparation group (experimental group):efferent loop stimulation
Preoperative Preparation group (experimental group):anal sphincter exercise
Routine waiting group (control group):Routine waiting
Sponsors
Peking University Cancer Hospital
Eligibility
Sex/Gender
Male
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 75 years; 2. ECOG Performance status 0-1; 3. Histologically confirmed diagnosis of adenocarcinoma of the rectum; 4. The distance from down verge of tumor to anal-rectal junction (ARJ) <=8cm based on MRI, or <=12 cm based on sigmoidoscopy; 5. Accepted neoadjuvant chemoradiotherapy before LAR; 6. Patients must read, agree to prior to participation in this study, and sign a statement of Informed Consent; 7. Preoperative endoscopy confirmed no anastomosis leakage before ileostomy closure; 8. Ileostomy was performed in LAR surgery and the ileostomy closure was completed in 6th month after operation.
Exclusion criteria
Exclusion criteria: 1. Live cirrhosis or malfunction of anticoagulation system; 2. Patients with any other concurrent medical or psychiatric condition or disease which would make them inappropriate candidates for entry into this study; 3. Recurrent rectal cancer.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sum of anastomotic stricture rate before ileostomy closure and rate of postoperative ileus after ileostomy closure.; | — |
Secondary
| Measure | Time frame |
|---|---|
| time to resume diet after ileostomy;time to resume diet after ileostomy;time in order to reduce postoperative complications;time of hospital stay;LARS score;Wexner score; | — |
Countries
China
Contacts
Public ContactZan Tiancheng
Peking University Cancer Hospital
Outcome results
None listed