allergic diseases
Conditions
Interventions
Intervention group:Preventive Antenatal Educational Program on Allergic Disease
Control group:Standard care
Sponsors
Beijing Daxing District People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Run-in phase inclusion criteria: 1. Enlisted in the birth registry of Daxing Teaching Hospital of Capital Medical University and intend to give birth at this location; 2. Women aged >=18 years; 3. Less than 14+6 gestational week when recruited as measured by last menstrual period; 4. Residents of Daxing and intend to remain residing in Daxing for at least two years postpartum; 5. Written consent form. Randomization phase inclusion criteria: 1. Enlisted in the birth registry of Daxing Teaching Hospital of Capital Medical University and intend to give birth at this location; 2. Less than 14+6 gestational week when recruited as measured by last menstrual period; 3. Residents of Daxing and intend to remain residing in Daxing for at least two years postpartum; Withdrawal criteria: 1. Still birth; 2. Abortion; 3. Rare comorbidities that present after inclusion into the study including but not limited to malignancies, amniotic fluid embolism, eclampsia, and major birth abnormalities of the child.
Exclusion criteria
Exclusion criteria: 1. Planned abortion; 2. Rare comorbidities of the mother that may cause miscarriage and congenital disabilities as determined by OBs, including but not limited to malignancies, congenital heart diseases, monogenetic diseases; 3. Recurrent miscarriage.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Whether there is atopic dermatitis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to first AD attack;Time of first topical corticosteroids;Infant quality of life evaluation;SCORAD score for severity of disease if AD is onset;AD episodes;Duration of onset of AD (IGA>=2 points) and time to disease-free (IGA<2 points);Is there a baby wheezing;Whether there is allergic rhinitis;Is there food sensitivity;Parents' awareness of allergic diseases, skin care procedures and hormones;Parental knowledge on skin care and atopic dermatitis;Asthma incidence;Cumulative clinical visit duration; | — |
Countries
China
Contacts
Public ContactXiuhua Ma
Beijing Daxing District People's Hospital
Outcome results
None listed