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To explore the optimal PEEP value of lung protective ventilation strategy under different positions during general anesthesia by the EIT

To explore the optimal PEEP value of lung protective ventilation strategy under different positions during general anesthesia by the EIT

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000040460
Enrollment
Unknown
Registered
2020-11-28
Start date
2020-12-01
Completion date
Unknown
Last updated
2021-03-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pulmonary complications

Interventions

Case series:different positions in general anesthesia

Sponsors

The Second Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. American Society of Anesthesiologists (ASA) Physical Status Level I - II; 2. aged 20 to 60 years old.

Exclusion criteria

Exclusion criteria: 1. Emergency surgery; 2. serious restrictive lung disease history, history of need oxygen severe chronic obstructive pulmonary disease (copd) (GOLD grade III or IV level), there are serious or not control of bronchial asthma, preoperative pulmonary infection in a month, bronchiectasis, lung metastases, preoperative use of positive pressure ventilation (such as obstructive sleep apnea syndrome of continuous positive airway pressure (cpap), thoracic deformity and intrathoracic diseases (such as mediastinal tumor and breast cancer), oxygen oxygen saturation of 95% or less; 3. Severe neuromuscular disease; 4. NYHA grade III or IV severe heart disease or acute coronary syndrome; 5. Persistent ventricular tachyarrhythmia; Cirrhosis of the liver (Child B or C); 6. glaucoma; 7. Chronic kidney failure requiring dialysis; 8. hemoglobin is below 10g/dl; 9. A pacemaker or other active surgical implant is installed; 10. PEEP titration cannot tolerate airway peak pressure (Ppeak) >40cmH2O; 11. Patients who refuse or cannot provide informed consent.

Design outcomes

Primary

MeasureTime frame
Best PEEP value;

Secondary

MeasureTime frame
blood pressure;heart rate;cardiac output;Peripheral vascular resistance;Stroke Volume VariationStroke volume variation;stroke volume;Pulse oxygen saturation;Cardiac circulation efficiency;Maximum rate of pressure rise;The airway peak pressure;Platform pressure;Mean airway pressure;pulmonary compliance;respiratory rate;tidal volume;minute ventilation;TINSP;Driving pressure;Regional tidal volume variation;

Countries

China

Contacts

Public ContactHuang He

The Second Affiliated Hospital of Chongqing Medical University

13708385559@163.com+86 13708385559

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026