gastric cancer
Conditions
Interventions
Case series:Enteral nutritional preparations should be used every day after surgery
Sponsors
The First Affiliated Hospital of Naval Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 75 years; 2. Postoperative pathology identified the patients as advanced stage (stage II and III); 3. Subject is malnourished or at risk of malnutrition (nutritional risk screening tool 2002 (nrs-2002) >=3 points); 4. Adjuvant chemotherapy is expected after surgery; 5. Laboratory tests were tolerant to surgery and chemotherapy; 6. Subject's life expectancy >=12 months; 7. Written informed consent can be obtained prior to randomization, and the patient should be aware that he or she has the right to withdraw from the study at any time without prejudice to subsequent treatment; 8. Subjects are willing to comply with the study protocol and are able and willing to ingest the study products according to the protocol; 9. Female subjects were not pregnant or at least 6 weeks postpartum and did not breastfeed.When screening, pregnant women of childbearing age should be examined to make sure there is no pregnancy; 10. Consent to provide hematological specimens.
Exclusion criteria
Exclusion criteria: 1. Subjects are not at risk of malnutrition or malnutrition (nutritional risk screening tool 2002 (NRS-2002) <3 points); 2. Postoperative patients are expected to be without chemotherapy; 3. Pregnant or nursing women; 4. For patients with uncontrolled epilepsy, central nervous system disease or mental disorder, the investigator shall determine whether the clinical severity of the disorder impedes the signing of informed consent or affects the patient's oral medication compliance; 5. If the subject has abnormal liver function or renal function, the doctor thinks that the subject cannot participate in the test; 6. The subject has severe cardiac insufficiency and is considered by the doctor to be unable to participate in the study; 7. Subjects have type 1 or type 2 diabetes (based on history and admission diagnosis, according to the study physician's opinion); 8. During the previous week, subjects had severe nausea, vomiting, and/or uncontrollable diarrhea/celiac dysentery (based on reported history or from the opinion of the study physician); 9. Subjects have a known history of dementia, brain metastases, eating disorders, significant neurological or psychiatric disorders, or have received antipsychotic treatment as a result of a mental illness statement; 10. The subject is known to have a history of allergy or intolerance to any ingredient in the test product; 11. Subjects are currently participating in or have participated in any other clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Degree of completion of chemotherapy; | — |
Secondary
| Measure | Time frame |
|---|---|
| BMI;NRS2002;progression free survival;overall survival; | — |
Countries
China
Contacts
Public ContactYin Kai
The First Affiliated Hospital of Naval Medical University
Outcome results
None listed