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Effect of programmed intermittent epidural bolus at different dosage regimens for labor analgesia: a randomized controlled trial

Effect of programmed intermittent epidural bolus at different dosage regimens for labor analgesia: a randomized controlled trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000040450
Enrollment
Unknown
Registered
2020-11-28
Start date
2020-12-01
Completion date
Unknown
Last updated
2021-11-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

labor analgesia

Interventions

Group 1:programmed intermittent epidural boluses 4ml/45min
Group 2:programmed intermittent epidural boluses 6ml/45min
Group 3:programmed intermittent epidural boluses 8ml/45min

Sponsors

Department of Anesthesiology, Affiliated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Maternal voluntary; 2. ASA I or II; 3. Full term (>=37 weeks gestation); 4. Singleton pregnancy, cephalic vaginal; 5. Nulliparous, NRS Pain score at requesting analgesia >5 (NRS 0-10); 6. Evaluated by obstetricians, vaginal delivery can be carried out (including scar uterus, gestational hypertension and preeclampsia, etc.).

Exclusion criteria

Exclusion criteria: 1. Any contraindication to epidural anesthesia: such as intracranial hypertension, abnormal blood coagulation, puncture site and systemic infection, as well as affecting the puncture operation; 2. Accidental dural puncture; 3. Allergy or hypersensitivity to bupivacaine or sufentanyl; 4. use of analgesics and sedatives for 2 weeks before delivery.

Design outcomes

Primary

MeasureTime frame
incidence of breakthrough pain;

Secondary

MeasureTime frame
NRS pain scores;Incidence of motor block;consumption of ropivacaine per hour during labor analgesia;Time of the first PCA;The time of the first stage of labor and the second stage of labor;

Countries

China

Contacts

Public ContactZhiping Wang

Department of Anesthesiology, Affiliated Hospital of Xuzhou Medical University

zhpxqst@163.com+86 13338787071

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026