Effect of Low Dose Flurbiprofen Ester on Postoperative Renal Function in Elderly Patients

Effect of Flurbiprofen Axetil on Postoperative Renal Function in Elderly Patients - A prospective, multicenter, randomized, double-blind, controlled clinical study

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000040435

Enrollment

Unknown

Registered

2020-11-28

Start date

2020-11-30

Completion date

Unknown

Last updated

2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Kidney Injury

Interventions

F:Preoperative injection flurbiprofen 100mg

C:Preoperative injection saline 10ml

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Aged 60 to 85 years; 2. ASA level 1-3; 3. Transurethral resection of prostate under intraspinal anesthesia; 4. BMI > 18 Kg/m2 and < 30 Kg/m2; 5. Written informed consent provided by the patient or his/her family members.

Exclusion criteria

Exclusion criteria: 1. Perioperative use of other nonsteroidal anti-inflammatory drugs; 2. Patients with cardiopulmonary insufficiency (echocardiogram: EF 1500 ml) Patients with low blood pressure (blood pressure lower than 90/60 mmmHg or MAP < 60 mmHg for more than 20 years) who need ICU treatment after surgery; 7. Patients with severe liver abnormalities (Pugh - C rating); 8. Patients have difficulty in visiting and Researchers withdrawing from septicemia, patients with septicemia or septicemia.

Design outcomes

Primary

Measure	Time frame
Ngal;IL-6;Scr;	—

Countries

China

Contacts

Public ContactLiao Qin

The Third Xiangya Hospital of Central South University

zhanghaoliaoqin@163.com+86 13787412348

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026