Graves’ ophthalmopathy
Conditions
Interventions
Gold Standard:Clinical outcomes
Index test:68Ga-DOTATATE 
SUVmax 
 
serum 
TSHR 
IGF-1R 
Sponsors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
14 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 14 to 65 years old; 2. Outpatients or inpatients in this hospital; 3. Frueh standard entry screening: 1) Patients have a history of thyroid disease, exophthalmos, protrusion >=20 mm, eyelid retraction, palpebral fissure enlargement by more than 11 mm, extraocular muscle involvement, at least one extraocular muscle is restricted For sexual lesions, CT examination showed that the extraocular muscles of one or both eyes were thickened; 2) 3 signs of exophthalmos/eyelid retraction/extraocular muscle involvement appeared, and at least 2 signs were bilateral; 3) exophthalmos/eyelid retraction /CT examination found that the extraocular muscles were thickened, and at least 1 of the 3 signs had more than 2 signs; 5. Patients need to agree to participate in the experiment and agree to sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Acute systemic diseases and electrolyte disorders; 2. Pregnant or lactating women; 3. Other patients who are not suitable for participating in the experiment (including PET/MR contraindications); 4. Patients who cannot be followed up as required during the study period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SUVmax;serum TSHR;serum IGF-IR; | — |
Countries
China
Contacts
Public ContactXiaotian Xia
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology (HUST)
Outcome results
None listed