primary total knee arthroplasty
Conditions
Interventions
Control group:Non-tranexamic acid
Sponsors
Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Osteoarthritis of the knee was diagnosed; 2. The primary unilateral total knee arthroplasty is planned; 3. The patients were randomly divided into groups according to whether tranexamic acid was applied during the operation and the time of drainage tube removal; 4. The observation indexes were set as the evaluation indexes of the degree of joint swelling and the curative effect.
Exclusion criteria
Exclusion criteria: 1. Patients choose to give up the operation before surgery; 2. With rheumatoid arthritis or other immune diseases; 3. Coagulation disorder; 4. Previous history of taking aspirin, Clopidogrel, warfarin and other anticoagulants; 5. combined with lower extremity venous thrombosis, obliterans; 6. Clearly allergic to tranexamic acid; Severe liver and kidney insufficiency; 7. Today complex knee varus, knee varus, such as the estimated operation time longer patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative drainage volume;total blood loss;Hidden blood loss;infection rate;Degree of postoperative swelling;ROM;VAS;HSS; | — |
Countries
China
Contacts
Public ContactFeng Shuo
Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed