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Prospective clinical study on the effect of mitomycin and glaucoma trabeculectomy on ocular surface

Prospective clinical study on the effect of mitomycin and glaucoma trabeculectomy on ocular surface

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000040409
Enrollment
Unknown
Registered
2020-11-28
Start date
2020-12-01
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

glaucoma

Interventions

Glaucoma trabeculectomy group:No intervention

Sponsors

The Second Xiangya Hospital of Central South
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) The patient must be at least 18 years old; (2) Having glaucoma and requiring trabeculectomy, the glaucoma specialist shall decide whether surgery is necessary; (3) No limitation on gender; (4) Voluntary investigation, no communication barriers

Exclusion criteria

Exclusion criteria: (1) Exclude patients with severe systemic diseases (such as sequelae of serious cerebrovascular accidents caused by cancer, vital organ failure, etc.); (2) Exclude any disease affecting the stability of tear film, including systemic diseases such as Sjogren's syndrome; (3) Exclude patients with other ocular surface diseases such as allergic bacterial virus; (4) Exclude patients with other eye diseases (except cataract) that affect visual function; (5) Patients with a history of eye surgery 1 year before trabeculectomy were excluded

Design outcomes

Primary

MeasureTime frame
tear protein;mRNA expression;

Countries

China

Contacts

Public ContactKe Liu

The Second Xiangya Hospital of Central South University

liukelc@126.com+86 1395806565

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026