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Study on local microbes before and after the operation of damp-heat anal fistula

Study on local microbes before and after the operation of damp-heat anal fistula

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000040395
Enrollment
Unknown
Registered
2020-11-28
Start date
2020-12-01
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anal Fistula

Interventions

Horseshoe Fistula:NA
Non-horseshoe Fistula:NA

Sponsors

Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Anal fistula group 1. Meet the diagnostic criteria of anal fistula; (1) Symptoms: recurring perianal swelling, pain and pus; (2) Physical examination: the appearance, position and discharge of the external opening can be seen. The induration and path of shallow anal fistula can be touched around the anus. Digital rectal examination can palpate the internal opening); 2. No surgical contraindications; 3. Aged 18 to 65 years old; 4. Join the trial voluntarily and sign the informed consent form. Healthy control group: 1. Aged 18 to 65 years; 2. Complete notification and informed consent.

Exclusion criteria

Exclusion criteria: Anal fistula group: 1. Have a history of severe anal surgery or trauma (except for the history of perianal abscess drainage); 2. Accompanied by systemic infections, gastrointestinal infectious diseases, psychosis, diabetes, severe cardiovascular diseases, coagulation dysfunction, rectal prolapse, rectovaginal fistula, and specific infections (tuberculosis, Crohn, ulcerative colitis Etc.), or anal fistula due to the rupture of a malignant tumor; 3. Have used antibiotics within 2 weeks before surgery. Healthy control group: 1. Suffer from acute and chronic diarrhea, systemic infections, digestive tract infectious diseases (tuberculosis, Crohn, ulcerative colitis, etc.), mental illness, diabetes, severe cardiovascular disease, coagulopathy, rectal prolapse; 2. Have a history of anal fistula and perianal abscess; 3. History of other serious anal surgery or trauma.

Design outcomes

Primary

MeasureTime frame
Flora;

Countries

China

Contacts

Public ContactQingMing Wang

Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine

davidwqm@163.com+86 13816903904

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026