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A real-world study of apatinib combined with TACE in patients with advanced liver cancer

A real-world study of apatinib combined with TACE in patients with advanced liver cancer

Status
Recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000040387
Enrollment
Unknown
Registered
2020-11-28
Start date
2020-11-28
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intermediate to advanced hepatocellular carcinoma

Interventions

Case series:apatinib

Sponsors

The First Affiliated Hospital of University of Science and Technology of China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients with hepatocellular carcinoma diagnosed clinically or histopathologically; 2. Aged >=18 years male or female; 3. Patients with BCLC stage B or C who cannot tolerate or refuse surgery (Schedule 1); 4. Child-pugh rating of liver function: Grade A or better Grade B (7 points); 5. ECOG score 0-2; 6. Patients who researchers believe could benefit

Exclusion criteria

Exclusion criteria: 1. Pregnant or lactating female patients; 2. Patients with apatinib or TACE treatment contraindications (such as: abnormal coagulation function, severe abnormality of liver, kidney and lung function, active bleeding, gastrointestinal ulcer, intestinal perforation or ileus, poorly controlled hypertension, etc.); 3. According to the judgment of the researcher, it is not suitable for the patients participating in this study.

Design outcomes

Primary

MeasureTime frame
PFS;

Countries

China

Contacts

Public ContactWeifu Lv

The First Affiliated Hospital of University of Science and Technology of China

alwf2020@163.com+86 13739268463

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026