Type 2 diabetes, non-alcoholic fatty liver disease
Conditions
Interventions
case series:none
Sponsors
School of Nursing, Jinan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: NAFLD: 1. According to the Chinese Guidelines for the Diagnosis and Treatment of Nonalcoholic Fatty Liver Disease (2010 Revised Edition): 1) no history of alcohol consumption or less than 140 g/week of alcohol consumption (female =11.1mmol/L(200mg/d)L); (2) fasting blood glucose (FPG) >=7.0 mmol /L; (3) glucose load after 2h blood glucose (2h PG) < 11.1mmol /L; (4) Patients without typical symptoms of diabetes.
Exclusion criteria
Exclusion criteria: 1. History of Alcohol intake>20g/d; 2. Co-existing of other liver diseases, such as viral, drug-induced, auto-immune hepatitis and so on; 3. Suspicion of liver cirrhosis or liver cancer; 4. Co-existing of other severe systematic disease or infectious disease, such as malignant neoplasm, severe cardiopulmonary disease, neurological disorders, HIV infection and so on; 5. Unable to control diet or to conduct aerobic exercise; 6. Currently pregnant, breastfeeding, pregnancy anticipated during study or planning to be conceive; 7. Co-existing of mental disorders or severe neurosis, or unable to express symptoms subjectively and hindering connection and cooperation with researchers because of dysgnosia or aphasis. 8. Exclude patients with type 1 diabetes 9. Exclude long-term insulin therapy and patients with suspicious autoimmune diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| liver function;blood lipids;Liver fat content(Quantitative ultrasound);blood inflammatory markers;Fasting Blood Glucose;Hemoglobin A1c (HbA1c); | — |
Countries
China
Contacts
Public ContactYinji Liang
School of Nursing, Jinan University
Outcome results
None listed