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Bilateral Limbal Stem Cells alterations in patients with unilateral herpes simplex keratitis with in vivo confocal microscopy clinical study

Bilateral Limbal Stem Cells alterations in patients with unilateral herpes simplex keratitis with in vivo confocal microscopy clinical study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000040372
Enrollment
Unknown
Registered
2020-11-28
Start date
2020-12-01
Completion date
Unknown
Last updated
2021-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infectious keratitis

Interventions

herpes simplex keratitis group:Nil

Sponsors

First Ward in Department of Ophthalmology, the First Affiliated Hospital of Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: patients aged 16 to 80 years with diagnosis of unilateral herpes simplex keratitis (HSK).

Exclusion criteria

Exclusion criteria: Subjects with any other comorbidities such as history of previous infectious keratitis, ocular inflammatory disease, ocular trauma, ocular surgery, or systemic disease known to affect the corneal epithelial healing or immunosuppression, other than diabetes or chronic corneal pathologies (cystic corneal disorders, epithelial basement membrane dystrophies).

Design outcomes

Primary

MeasureTime frame
Palisades of Vogt;corneal epithelial cells;corneal basal nerve;—

Countries

China

Contacts

Public ContactHong Zhang

First Ward in Department of Ophthalmology, the First Affiliated Hospital of Harbin Medical University

18846081489@163.com+86 18846081489

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026