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Prospective study of two-dimensional speckle tracking imaging in early diagnosis and prognosis evaluation of MM associated CA

Prospective study of two-dimensional speckle tracking imaging in early diagnosis and prognosis evaluation of MM associated CA

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000040356
Enrollment
Unknown
Registered
2020-11-28
Start date
2020-09-11
Completion date
Unknown
Last updated
2021-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cardiac amyloidosis

Interventions

Gold Standard:external cardiac biopsy
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Sponsors

The Second Affiliated Hospital of Army Medical University, PLA
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Clinically confirmed multiple myeloma with positive Congo red staining by extracardiac biopsy; 2. No clinical treatment related to multiple myeloma has been performed; 3. No other history of chemotherapy with anthracyclines for malignant tumors; 4. Good compliance, no mental disorder; 5. Willing to participate in this study and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. No extracardiac biopsy results; 2. Patients with hypertension and secondary cardiac hypertrophy caused by moderate aortic valve disease; 3. Receiving other anticancer drugs (chemotherapy drugs such as anthracyclines that are clearly harmful to the heart muscle); 4. Cannot cooperate with the study or the researcher considers it inappropriate to be included in this study.

Design outcomes

Primary

MeasureTime frame
Left ventricular mass index;Left ventricular ejection fraction;Left ventricular longitudinal strain;Left ventricle longitudinally stratified strain;The radial strain;Circumferential strain;

Countries

China

Contacts

Public ContactXu Yali

The Second Affiliated Hospital of Army Medical University, PLA

xuyali1976@163.com+86 18523384936

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026