IgA nephropathy
Conditions
Interventions
Case series:Nil
Sponsors
Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged not less than 14 years old, female and male; 2. Clinical and biopsy-based diagnosis of primary IgA nephropathy; 3. Adequate biopsy sample with not less than 10 glomeruli; 4. Patients with eGFR not less than 30ml/min/1.73m2 (estimated by CKD-EPI formula in 2009); 5. Sign the informed consent form in accordance with the regulations, and patients under the age of 18 need to have a legal guardian to sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Secondary IgA nephropathy caused by diabetes, systemic lupus erythematosus, Henoch-Schonlein purpura,viral hepatitis,liver cirrhosis, etc; 2. Patients with malignant tumors; 3. Patients with kidney transplantation; 4. Pregnancy; 5. Disagree to participate in the study or poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 50% reduction in the eGFR compared to baseline;all-cause death;Need for dialysis therapy;The rate of decline in the eGFR;variations in urine protein excretion rate; | — |
Countries
China
Contacts
Public ContactQiongqiong Yang
Sun Yat-sen Memorial Hospital, Sun Yat-Sen University
Outcome results
None listed