postoperative pulmonary complications
Conditions
Interventions
control group:VT=8ml/kg, PEEP=5cmH2O
control group:VT=6ml/kg, PEEP=5cmH2O
trial group:VT=8ml/kg, The best PEEP titrated by driving pressure
trial group:VT=6ml/kg, The best PEEP titrated by driving pressure
Sponsors
The First People's Hospital of Yunnan Province
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) ASA I/II without important organ disease; (2) Laparoscopic gynecological surgery under elective general anesthesia and high head and foot position.
Exclusion criteria
Exclusion criteria: (1) chest X-ray or CT indicates pulmonary injury such as emphysema, severe pulmonary bullae, pneumothorax and so on; (2) septicemia or severe infection; (3) Neuromuscular diseases; (4) concomitant with severe pulmonary hypertension, intracranial hypertension and other contraindications for redilation of the lung.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the incidence of PPCs with 7 days after operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Dead space ratio;Oxygenation index;concentration of IL-1, IL-6, TNF-alpha, CRP; | — |
Countries
China
Contacts
Public ContactRui Liu
The First People's Hospital of Yunnan Province
Outcome results
None listed