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The efficacy and safety of apatinib in the treatment of locally advanced or recurrent and metastatic gynecologic tumors: a real world study.

The efficacy and safety of apatinib in the treatment of locally advanced or recurrent and metastatic gynecologic tumors: a real world study.

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000040335
Enrollment
Unknown
Registered
2020-11-28
Start date
2020-11-20
Completion date
Unknown
Last updated
2021-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gynecologic tumors

Interventions

Case series:apatinib

Sponsors

Shandong Provincial Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1) Aged >=18 years old female; 2) Patients were confirmed locally advanced or advanced recurrent or metastatic ovarian cancer, fallopian tube cancer, endometrial cancer and cervical cancer confirmed by histopathology and / or cytology; 3) The subjects volunteered to join the study, signed the informed consent form, had good compliance and cooperated with the follow-up; 4) Women of childbearing age must have a pregnancy test (serum) within 7 days before enrollment, and the results are negative, and they are willing to use appropriate contraceptive methods during the trial and within 8 weeks after the last administration of the trial drug; 5) The researchers believe who will be able to get benefit.

Exclusion criteria

Exclusion criteria: 1) Radical operation was feasible except for patients with tumor reduction; 2) Pregnant or lactating women; 3) Allergy to apatinib and / or its excipients; 4) Patients with contraindications to apatinib; 5) Other situations that are not suitable for inclusion in this study according to the researcher's judgment; 6) Patients who are participating in other clinical trials are not suitable for this trial

Design outcomes

Primary

MeasureTime frame
PFS;

Countries

China

Contacts

Public ContactChangzhong Li

Shandong Provincial Hospital

15662629180@163.com+86 15662629180

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026