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A multi-center clinical study for application of artificial intelligence-based noninvasive coronary artery physiological function assessment technique in the diagnosis and treatment of chronic coronary syndrome

A multi-center clinical study for application of artificial intelligence-based noninvasive coronary artery physiological function assessment technique in the diagnosis and treatment of chronic coronary syndrome

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000040304
Enrollment
Unknown
Registered
2020-11-27
Start date
2020-11-20
Completion date
Unknown
Last updated
2021-02-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic cardio-cerebrovascular syndrome

Interventions

Index test:CTFFR

Sponsors

Sichuan Provincial People’s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: Age 18 or older, male or non-pregnant; understand and voluntarily sign an informed consent form approved by the ethics committee; be able to undergo coronary CTA scans, invasive ICA and FFR tests; Be Able to comply with the research procedures specified in the programme.

Exclusion criteria

Exclusion criteria: 1. The patient has a history of PCI; the patient has a past history of CABG; 2. the patient has contraindications to receptor blockers, nitrates, Adenosine, and iodine; 3. the patient has long QT syndrome, severe hypertension; 4. patients with severe asthma, severe chronic obstructive pulmonary disease, or Bronchodilator-dependent chronic obstructive pulmonary disease are highly suspected of Acute Coronary Syndrome (ACS), including acute myocardial infarction and unstable coronary heart disease; 5. the patient had myocardial infection within 30 days before and after coronary CTA; 6. The patient had a definite history of complex congenital heart defect; 7. The patient had received artificial pacemaker or implantable, defibrillator electrodes; 8. Patients had undergone prosthetic heart valve implantation; 9. patients had tachycardia or significant arrhythmias; 10. patients had abnormal liver and renal function; 11. patients had a body mass index (BMI)>35; 12. The clinical manifestations of the patients indicate an acute unstable state, including acute chest pain (sudden onset), cardiac origin, sexual Shock, unstable blood pressure (systolic blood pressure less than 90 MMHG) and severe heart failure (NYHA Grade III to IV) or acute pulmonary edema; 13. There are any other factors that the researchers considered unsuitable for inclusion or completion of the study.

Design outcomes

Primary

MeasureTime frame
FFR;

Countries

China

Contacts

Public ContactCheng Biao

Sichuan Provincial People's Hospital

chengbiao9297@163.com+86 18981838867

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026