Liver cirrhosis
Conditions
Interventions
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 75 years; 2. Diagnosed with liver cirrhosis; 3. Receive elective TIPS.
Exclusion criteria
Exclusion criteria: 1) Previous treatments with TIPS or surgical shunt; 2) History of hepatic encephalopathy or hepatic encephalopathy diagnosed at enrollment; 3) Hepatic myelopathy or other neuropsychological disorders; 4) Prescribed with medical enternal or parenternal nutrition, antibiotics, or lactulose within 4 weeks before enrollment; 5) Gastrointestinal bleeding, spontaneous bacterial peritonitis, hepatorenal syndrome or hepatopulmonary syndrome is uncontrolled or stable less than 1 week; 6) Vital organ insufficiency (heart, lung, kidney, brain, etc.); 7) Incompetent of reading due to compromised vision; 8) Poor literacy to recognize, comprehend and write simple words; 9) Residency in high altitudes (higher than 2500 meters above the sea level); 10) In pregnancy or lactation; 11) Child-Pugh score exceeds 12 points or aminotransferase elevations exceeds five times of upper limits of normal; 12) Cholestatic diseases (primary biliary cirrhosis, primary sclerosing cholangitis, extrahepatic bile duct obstruction, etc.); 13) Presence of malignancy; 14) Portal cavernoma.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Metabonomics; | — |
Countries
China
Contacts
Public ContactHao Wu
West China Hospital, Sichuan University
Outcome results
None listed