Effects of fluid optimization before induction of general anesthesia and intraoperative goal-directed therapy on the outcomes of elderly patients

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000040269

Enrollment

Unknown

Registered

2020-11-26

Start date

2021-02-20

Completion date

Unknown

Last updated

2024-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Operation for elderly patients

Interventions

control group:Routine anesthesia management

intervention group:Liquid optimization combined with goal-directed therapy

Eligibility

Sex/Gender

All

Age

65 Years to No maximum

Inclusion criteria

Inclusion criteria: 1) Aged>65 years; 2) ASA classification I-II; 3) Elective radical surgery for gastric cancer under general anesthesia

Exclusion criteria

Exclusion criteria: 1) BMI>35 kg?m-2; 2) Liver and kidney dysfunction; 3) Heart failure; 4) Active atrial fibrillation; 5) Significant aortic or mitral regurgitation; 6) Diabetes or peripheral vascular disease; 7) Increased intra-abdominal pressure.

Design outcomes

Primary

Measure	Time frame
Acute kidney injury;Quality of recovery-15 items;Hemodynamic instability induced by general anesthesia induction;	—

Secondary

Measure	Time frame
Respiratory complications;Intraoperative fluid intake and output;Postoperative nausea and vomiting;Surgical site infection;Hyperlactic acidemia;Awake time, extubation time;Tissue oxygen saturation;Hospitalization time;	—

Countries

China

Contacts

Public ContactTian Dandan

The First Affiliated Hospital of Zhengzhou University

ddt0802@163.com+86 13939071527

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026