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The addition of dexamethasone to local infiltration analgesia during selective joint arthroplasty: a double-blind randomized controlled trial

The addition of dexamethasone to local infiltration analgesia during selective joint arthroplasty: a double-blind randomized controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000040234
Enrollment
Unknown
Registered
2020-11-25
Start date
2020-11-21
Completion date
Unknown
Last updated
2021-02-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain and joint

Interventions

control group:LIA?2mL??????0.9%
Experimental group:LIA mixed with 2mL of dexamethasone 4mg/mL

Sponsors

Affiliated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: We included male and female, American Society of Anesthesiologists physical status 1 to 4 patients, aged 18 to 85 years, weighing 50 to 100kg, with a body mass index of 18 40kg/m2, and undergoing elective primary, unilateral joint arthroplasty under spinal anesthesia.

Exclusion criteria

Exclusion criteria: Exclusion criteria were revision or bilateral arthroplasty procedures, contraindications to spinal anesthesia, intraoperative general anesthesia, allergy to any of the study medications, chronic pain state or opioid dependence unrelated to hip pathology (defined as ongoing requirement of opioids for analgesic management of any ongoing pain state that is unrelated to hip pathology for longer than 12 weeks), and significant peripheral neuropathy.

Design outcomes

Primary

MeasureTime frame
opioid consumption;

Secondary

MeasureTime frame
Functional outcomes;complication;pain scores at rest (A) and with activity (B);TUG;ROM;Distance walked;

Countries

China

Contacts

Public ContactFeng Shuo

Affiliated Hospital of Xuzhou Medical University

xzfs0561@163.com+86 18552880088

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026