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Effect of noradrenaline on umbilical blood flow for hypotension after spinal anesthesia during cesarean section in severe preeclampsia

Effect of noradrenaline on umbilical blood flow for hypotension after spinal anesthesia during cesarean section in severe preeclampsia

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000040221
Enrollment
Unknown
Registered
2020-11-25
Start date
2020-11-20
Completion date
Unknown
Last updated
2021-02-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypotension after anesthesia

Interventions

Hypotension group:Treatment of hypotension with noradrenaline
Group without hypotension:No treatment

Sponsors

The Sixth People’s Hospital of Hui Zhou
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 35 Years

Inclusion criteria

Inclusion criteria: (1) Meet the diagnostic criteria of severe preeclampsia; (2) ASA II/III; (3) Aged 20 to 35 year; (4) BMI 36 weeks; (6) Hb>=90g/L-1.

Exclusion criteria

Exclusion criteria: (1) Liver and kidney function is obviously abnormal before operation; (2) Hypertension complicated with pregnancy; (3) Complicated with diabetes or other metabolic diseases; (4) Respiratory failure or heart failure before operation; (5) Anesthesia level is lower than T10 or higher than T6.

Design outcomes

Primary

MeasureTime frame
Peak systolic velocity (psv);End diastolic velocity (edv);resistance index (RI);systolic peak velocity/diastolic velocity (S/D);

Secondary

MeasureTime frame
Blood gas analysis parameters of umbilical artery;Blood gas analysis parameters of umbilical vein;Neonatal Apgar score;

Countries

China

Contacts

Public ContactWenkai Wang

Department of Anesthesiology, The Sixth People's Hospital of Huizhou

mywenkai@163.com+86 13923612371

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026